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Updated: Jul 13, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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设计,合成和强大的抗癌活动的新型Indole-based Bcl-2 抑制剂的设计,合成和强大的抗癌活性

Ahmed M Almehdi1,2, Sameh S M Soliman3,4, Abdel-Nasser A El-Shorbagi4

  • 1College of Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.

International journal of molecular sciences
|October 14, 2023
PubMed
概括

新的以醇为基础的化合物显示出作为向BCL-2蛋白的抗癌剂的希望. 化合物U2有效抑制癌细胞生长,诱导细胞灭绝,并停止细胞循环,具有有利的安全性.

关键词:
Bcl-2 的使用方法.抗亡蛋白质是一种抗亡蛋白质.癌症药物发现的发现印度尔 (Indole) 是一种制剂.

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