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Updated: Jul 13, 2025

A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9
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通过双重方法探索PCSK9对脂蛋白的遗传影响:关联和门德尔随机化

Ya-Ching Chang1, Lung-An Hsu2, Yu-Lin Ko3

  • 1Department of Dermatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Tao-Yuan 33305, Taiwan.

International journal of molecular sciences
|October 14, 2023
PubMed
概括

PCSK9 E670G基因变异与较低的脂蛋白 (Lp) 水平有关. 门德尔随机化证实PCSK9水平和Lp (a) 度之间的因果关系,影响心血管风险.

关键词:
门德尔的随机化在PCSK9基因.脱脂血症是什么情况超脂蛋白血症 (a) 是指高脂蛋白血症的发生.脂蛋白 (a) 是一种蛋白质多形态主义的多态主义.

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