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Updated: Jul 13, 2025

CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery
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CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery

Published on: May 30, 2025

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克里斯普尔/dCas9工具:表观遗传机制和在基因转录调节中的应用

Ruijie Cai1,2, Runyu Lv1,2, Xin'e Shi1,2

  • 1Laboratory of Animal Fat Deposition and Muscle Development, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.

International journal of molecular sciences
|October 14, 2023
PubMed
概括

基因编辑CRISPR/Cas9可以改变基因组的稳定性. 修改后的CRISPR (dCas9) 工具,如CRISPRa和CRISPRi,通过准表观遗传修改来实现精确的基因调控,为研究和疾病治疗提供新的途径.

关键词:
在CRISPR中激活CRISPR.抑制了CRISPR的发生.通过DNA甲基化.基斯顿基因基因基因基因基因基因基因基因基因基因基因基因基因转录条例 转录条例 转录条例

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