益生菌和益生菌:治疗非酒精性脂肪肝疾病的治疗工具
Alejandra Mijangos-Trejo1, Natalia Nuño-Lambarri1, Varenka Barbero-Becerra1
1Médica Sur, Mexico City 14050, Mexico.
International journal of molecular sciences
|October 14, 2023
概括
益生菌和益生菌在通过改善肠道健康来治疗非酒精性脂肪性肝病 (NAFLD) 方面表现有前途. 这些干预措施有助于恢复肠道微生物群和屏障功能,可能减少肝脏脂肪积累.
科学领域:
- 胃肠病学和肝病学 胃肠学和肝病学
- 微生物学 微生物学
- 代谢疾病 代谢疾病
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 的发病与肠肝轴功能障碍和改变的肠道微生物群有关.
- 患有NAFLD的患者经常表现出小肠细菌过度生长和肠道透性增加.
研究的目的:
- 审查益生菌和益生菌用于管理NAFLD的治疗潜力.
- 总结关于调节肠道微生物群以改善NAFLD结果的证据.
主要方法:
- 这是一个叙述性综述,总结了现有的体内和体外研究.
- 专注于研究研究益生菌,特别是 * Lactobacillus * 和 * Bifidobacterium * 种类.
主要成果:
- 益生菌干预已在NAFLD的动物模型中显示出有益的影响.
- 益生菌可以帮助恢复肠道微生物群平衡,增强肠道屏障的完整性.
结论:
- 益生菌和益生菌代表了NAFLD有前途的治疗途径.
- 调节肠道微生物群可能是改善肝脏脂肪积累和NAFLD整体管理的关键.
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