恢复性牙树脂与甲酸盐功能化,具有氧酸盐重矿化能力
Xin Zhang1, Yuxuan Zhang2, Ying Li1
1College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, China.
Materials (Basel, Switzerland)
|October 14, 2023
概括
通过光聚合,开发了一种新型的牙科修复材料,其中包含甲酸盐 (CMA). 这种材料有效诱导酸 (HA) 矿化,显示出牙科应用的前景.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料工程 牙科材料工程
- 纳米技术 纳米技术
背景情况:
- 诱导类似质的酸 (HA) 矿化对于牙修复材料至关重要.
- 传统的牙科树脂缺乏固有的矿化能力.
研究的目的:
- 开发一种新型的,富含的牙修复材料,具有in situ HA矿化能力.
- 为了研究甲酸盐 (CMA) 对材料性能和矿物化的影响.
主要方法:
- 含有Bis-GMA,TEGDMA和CMA的树脂配方的光聚合.
- 使用实时FTIR分析光聚化动力学.
- 机械性能 (压缩模量) 和表面形态 (SEM,X射线光谱) 的评估.
- 在现场评估HA矿化和生物相容性 (MTT测定,细胞附着).
主要成果:
- 这种新型牙科树脂 (BTCM) 是通过简单的一步光聚合制备的.
- 增加的CMA含量降低了压缩模量,但增强了HA晶体形成.
- 在浸泡后,在含有CMA的树脂的表面观察到密集的HA晶体.
- BTCM表现出良好的生物相容性,并支持L929细胞粘附和增殖.
结论:
- 开发的富牙树脂 (BTCM) 有效地诱导酸矿化.
- 该材料具有良好的机械性能和出色的生物相容性.
- 这种简单,具有成本效益的方法具有临床牙科应用的潜力.
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