定期有氧运动对改善韩国老年妇女血管硬的有效性
Suhan Koh1, Taekyu Kim1, Duwang Kang1
1Department of Physical Education, Pusan National University, Busan 46241, Republic of Korea.
Journal of clinical medicine
|October 14, 2023
概括
定期的有氧运动显著改善了血管硬性,并降低了老年妇女心血管疾病的风险因素. 一项为期16周的计划对动脉对大腿脉冲波速 (cf-PWV) 和细胞粘附分子产生积极影响.
科学领域:
- 老年学和运动生理学
- 心血管健康和疾病预防
背景情况:
- 血管硬和内皮功能障碍是老年人心血管疾病的重要危险因素.
- 有氧运动是一种潜在的非药物干预,可以缓解血管衰老.
- 对于有氧运动对老年妇女血管硬标志物和细胞粘附分子的具体影响,研究有限.
研究的目的:
- 调查16周有氧运动计划对老年妇女动脉到大腿脉冲波速 (cf-PWV) 和细胞粘附分子 (ICAM-1,VCAM-1,E-selectin) 的影响.
- 评估cf-PWV变化与血管炎症和内皮功能障碍的标志物之间的相关性.
- 为了确定有氧运动对氧化LDL水平的影响,在这个人群中.
主要方法:
- 进行了为期16周的有氧运动干预.
- 参与者 (n=40,70-85岁) 被分为血管硬,肥胖和正常的组.
- 在干预前和后收集了cf-PWV,ICAM-1,VCAM-1,E-selectin和氧化LDL的数据,并使用ANOVA和相关性分析进行了分析.
主要成果:
- 在运动干预后,观察到cf-PWV,VCAM-1,E-selectin和氧化LDL的显著相互作用效应.
- cf-PWV的变化率与VCAM-1和氧化LDL的变化呈正相关.
- 回归分析表明,cf-PWV的变化解释了VCAM-1的12.4%和氧化LDL的10.6%的变异.
结论:
- 一项为期16周的有氧运动计划有效地改善了韩国老年妇女的血管硬性,并降低了关键的心血管风险标志物.
- 这些发现表明,有氧运动可以减轻血管功能障碍,并可能降低动脉样硬化和相关心血管疾病的风险.
- 在老年人中,定期运动在保护血管内皮细胞功能方面发挥了积极作用.
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