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电化学疗法治疗骨转移:一个系统性审查
Maria Beatrice Bocchi1,2, Cesare Meschini1,2, Silvia Pietramala1,2
1Department of Orthopaedics, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Journal of clinical medicine
|October 14, 2023
概括
电化疗有效治疗骨转移,稳定了超过一半的患者的疾病,并显著减少疼痛. 这种最少的侵入性方法可以改善骨参与的癌症患者的生活质量.
科学领域:
- 在瘤学瘤学.
- 抚慰性护理是一种缓解性护理.
- 最少侵入性手术的方法
背景情况:
- 骨干涉显著影响癌症患者的预后和生活质量.
- 电化学疗法是一种缓和的,最少的侵入性治疗,最初用于皮下瘤.
- 骨转移代表了癌症护理中的一个关键挑战.
研究的目的:
- 系统地审查和评估电化学疗法在治疗骨转移中的疗效.
- 为了评估瘤反应和疼痛管理在接受电化学治疗骨转移的患者.
主要方法:
- 对PubMed MEDLINE和科克莱恩图书馆数据库的系统文献综述.
- 包括关于尾骨转移的皮肤间电化学疗法的研究.
- 遵循系统审查和元分析 (PRISMA) 准则的首选报告项目.
主要成果:
- 分析了8篇文章,涉及246名患者和250个骨损伤.
- 根据RECIST标准,在55.5%的患者中观察到疾病稳定.
- 平均疼痛评分 (VAS) 治疗后从6.9降至2.7,不良事件发生率为3.4%.
结论:
- 电化疗是一种可行的,节省组织的选择,用于管理骨转移.
- 考虑为患者提供电化学疗法,其选择有限,以实现瘤控制和提高生活质量.
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