胃肠炎和母亲:通过受孕,怀孕和超越的旅程
Antonio M Caballero-Mateos1, Miguel Quesada-Caballero2, Guillermo A Cañadas-De la Fuente3
1Gastroenterology Unit, Internal Medicine Department, Hospital Santa Ana, 18600 Motril, Spain.
Journal of clinical medicine
|October 14, 2023
概括
患有炎症性肠病 (IBD) 的女性怀孕存在风险,但积极管理和安全的药物使用可以改善结果. 在怀孕和母乳养期间继续治疗IBD通常是安全的,减少了母亲和孩子的并发症.
科学领域:
- 胃肠道学和产科 产科
- 生殖医学 生殖医学
- 免疫学 免疫学 免疫学
背景情况:
- 炎症性肠病 (IBD) 显著影响母亲的健康和怀孕结果.
- 患有IBD的女性怀孕带来了独特的临床挑战和风险.
研究的目的:
- 审查有关IBD妇女怀孕的科学证据.
- 为怀孕期间管理IBD提供基于证据的建议.
主要方法:
- 对科学数据库进行全面的文献搜索.
- 包括临床研究,系统审查和相关资源.
- 对IBD怀孕中母亲和婴儿结局数据的分析.
主要成果:
- 在IBD怀孕中,早产,低出生体重和先天性形的风险增加.
- 在怀孕和母乳养期间,继续服用提奥普林,抗TNF,维多利祖马布和乌斯特基努马布是安全的.
- 由于感染风险,建议在联合治疗时谨慎使用;小分子是禁忌的.
结论:
- 在怀孕前和怀孕期间,积极的IBD管理对于降低风险至关重要.
- 跨学科的护理和尽量减少疾病活动对于最佳的结果至关重要.
- 需要进一步的研究才能充分了解IBD对怀孕和婴儿健康的影响.
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