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评估低质量的胚胎移植和预后参数后的临床结果

Nezaket Kadioglu¹, İnci Kahyaoğlu², İskender Kaplanoğlu²

¹Department of Obstetrics and Gynecology, University of Yuksek Ihtisas, Ankara 06530, Turkey.

Journal of clinical medicine

|October 14, 2023

概括

即使是低质量的胚胎移植,成功的活产是可能的. 这项研究发现,每次临床怀孕的活产率很高,当只有低质量的胚胎可用时,这是一种可行的选择.

科学领域:

生殖医学生殖医学
胚胎学胚胎学
在体外受精过程中受精.

背景情况:

评估低质量的胚胎移植的临床结果对于优化辅助生殖技术至关重要.
了解预后因素可以改善试管婴儿患者的咨询和治疗策略.

研究的目的:

调查质量差的胚胎移植的临床结果.
确定可以预测这种转移的预后的参数.
为了比较低质量和高质量胚胎移植之间的结果.

主要方法:

对2123个涉及新鲜胚胎移植 (3日和5日) 的试管婴儿周期的回顾性分析.
低质量和高质量胚胎移植组之间的临床结果的比较.
基于胚胎移植日和与人口和刺激参数相关的子组分析.

主要成果:

在质量差的胚胎移植中,有14.9%的胚胎获得了临床怀孕,每次临床怀孕的活产率为67.9%.
临床怀孕的活产率在质量差的胚胎细胞移植中高于分裂阶段的胚胎.
增加的总性腺激素剂量与低质量的胚胎组中减少活产概率和hCG阳性相关.

结论:

质量差的胚胎移植虽然有较低的怀孕率,但一旦怀孕确立,可以产生高的活产率.
当没有优质胚胎可用时,转移质量差的胚胎可能是一个可接受的策略.
预后因素,如淋巴激素剂量,需要进一步调查与低质量的胚胎移植结果有关.

关键词:

淋巴激素的剂量淋巴激素的剂量在体外受精体外受精.活生生的出生率是多少胚胎质量不佳的胚胎质量很差

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