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在皮肤性心房 Septal 缺陷关闭后 GCO 装置在儿科人口中进行中期电力改造

Jennifer Fumanelli¹, Silvia Garibaldi^2,3, Biagio Castaldi¹

¹Pediatric Cardiology Unit, Woman's and Child's Health Department, Padua University, 35122 Padova, Italy.

Journal of clinical medicine

|October 14, 2023

概括

使用GORE CARDIOFORM隔膜封闭器通过皮肤关闭心脏隔膜缺陷,可显著改善心脏电活动,并减少儿科患者的右心脏大小. 这些积极的变化是长期持续的.

科学领域:

心脏病学心脏病学
儿童心脏病学儿童心脏病学
医疗器械医疗器械

背景情况:

由于其灵活性,GORE CARDIOFORM (GCO) 隔膜封闭器在心房隔膜缺陷 (ASD) 和圆孔关闭方面提供了理论上的优势.
评估GCO设备对儿童心电学参数的影响至关重要.

研究的目的:

在小儿科队列中,用GCO装置进行皮肤穿透ASD关闭后评估短期和中期心电图 (ECG) 变化.
为了将心电图发现与心脏结构变化相关联.

主要方法:

39名患有孤立自闭症的儿科患者使用GCO装置进行过导管关闭.
电子心电图被记录在手术前,24小时后和手术后6个月.
分析了P波分散,QTc间隔,QTc分散和心脏频率;在6个月后进行了霍尔特监测.

主要成果:

在手术后24小时内观察到P波分散,PR导电和QTc分散的显著改善.
在6个月后,QTc间隔显著减少.
心脏频率在6个月内显著下降,没有检测到主要心律失常.
在6个月后,ASD关闭导致右心尺寸和体积显著减少.

结论:

用GCO装置进行皮肤穿的ASD关闭,可以快速提高心脏内的电同质性.
这些电力效益是长期维持的,并且与正面的右心脏重塑有关.
在儿童ASD患者中,GCO设备在改善电功能和心脏结构方面表现出有效性.

关键词:

在GORE® Cardioform ASD Occluder 设备中,我们可以使用 P波的分散是P波的分散.在QTc分散的分散.节律失常可能是心律失常.心房隔膜缺陷 (ASD) 是一种心房缺陷.心脏电气改造的心脏电气改造

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