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Updated: Jul 13, 2025

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在瘤进展和转移中,YAP/TAZ信号网络的多功能调节

Hannah L Thrash1, Ann Marie Pendergast1

  • 1Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA.

Cancers
|October 14, 2023
PubMed
概括

河马通路蛋白YAP和TAZ通过调节基因表达来驱动瘤生长,转移和治疗抵抗. 针对这些联合激活剂为治疗固体瘤提供了新的策略.

关键词:
取决于 TEAD 的转录.在 YAP/TAZ 信号系统中.治疗策略 治疗策略转录的目标.瘤转移的发生.

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