在65岁以上的患者内镜下粘膜切除后,萨科佩尼亚对肺炎的影响:一项回顾性研究
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Updated: Jul 13, 2025

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
Published on: February 21, 2025
Min-Yu Kim1, So Yeon Kim1, Hye Jung Shin2
1Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
在老年人体内,在内镜下粘膜切割 (ESD) 后,肉类缩症会增加肺炎的风险. 将肉类与73岁以上的年龄结合起来,可以确定ESD后肺炎的高风险患者.
科学领域:
- 胃肠病学 胃肠病学
- 老年病的医生 老年病的医生
- 肺部病理学 肺部病理学
背景情况:
- 内镜下粘膜切割 (ESD) 是胃瘤的常见手术.
- 肺炎是ESD后的潜在并发症,特别是在老年患者中.
- 随着年龄的增长而导致的肌肉质量损失 - - 萨尔科佩尼亚 (Sarcopenia) 可能会影响术后的结果.
研究的目的:
- 调查65岁及以上患者在ESD后的萨尔科佩尼亚和肺炎发病率之间的关联.
- 在该患者群体中确定ESD后肺炎发展的风险因素.
主要方法:
- 回顾性队列研究,包括为胃瘤接受ESD的患者.
- 患者根据肉类的存在或不存在来对患者进行分类.
- 倾向分数匹配 (PSM) 用于在组之间平衡基线特征 (1:1比率).
- 主要终点是ESD后肺炎的发病率.
主要成果:
- 在ESD后肺炎的总发病率为2.2%.
- 在PSM之后,与没有sarcopenia的患者相比,sarcopenia患者的肺炎发病率显著更高 (p = 0.024).
- ,特别是与年龄≥73岁 (OR = 3.92) 相结合,显著与肺炎风险增加有关.
- 萨科佩尼亚也与较高的白细胞症和更长的住院时间有关.
结论:
- 在老年患者中,sarcopenia是ESD后肺炎的独立风险因素.
- 麻症和晚年 (≥73岁) 的结合是识别高风险个体的有效预测因素.
- 这些发现表明,在接受ESD的老年患者中评估类病状况的重要性,以减轻术后肺炎的风险.
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