几种大形式的抗氧化和抗增殖活动
Zeinab Farhat1, Tyler Scheving2, Diana S Aga2
1Department of Epidemiology and Environmental Health, State University of New York at Buffalo, Buffalo, NY 14260, USA.
Nutrients
|October 14, 2023
概括
大 大 大 大 大
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 生物化学 生物化学
背景情况:
- 氧化应激与细胞损伤和癌症等疾病有关.
- 人们假设大 (Allium sativum) 可以提供对氧化应激的保护.
- 不同的制剂对其抗氧化和抗癌特性的影响尚不清楚.
研究的目的:
- 为了比较各种大形式的体外抗氧化和抗增殖活性.
- 为了研究准备和加工如何影响大的潜在健康益处.
主要方法:
- 使用DPPH,超氧化物和基基清除试验评估抗氧化活性.
- 通过SRB测定评估了对肺癌细胞系 (H520,H1975,A549) 的抗增殖作用.
- 从新鲜,加热,粉末,黑和补充剂中测试水和酒精提取物.
主要成果:
- 补充剂Garlicin®在水和酒精提取物中显示出高的抗氧化活性.
- 新鲜大水提取物 (粉碎并置于一边) 显示出最高的基清除活性.
- 大酒精提取物和新鲜大水提取物显著抑制了肺癌细胞的增殖.
- 大粉和黑大的抗氧化和抗增殖作用较低.
结论:
- 大的制备和加工显著影响其抗氧化和抗增殖潜力.
- 某些形式的,如新鲜的提取物和特定的补充剂,在体外显示有前途的抗癌活性.
- 进一步研究优化大加工以获得治疗效益是有必要的.
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