血清维生素D3 中国老年人集中度,睡眠和认知障碍
Yuning Xie1, Chen Bai1, Qiushi Feng2
1School of Labor and Human Resources, Renmin University of China, Beijing 100872, China.
Nutrients
|October 14, 2023
概括
足够的维生素D3 (25(OH) D3) 水平和良好的睡眠质量与老年人认知能力下降的风险较低有关. 足够的维生素D3可能会增强这些保护作用,特别是正常睡眠时间.
科学领域:
- 老年学是一门学科.
- 营养神经科学 营养神经科学
- 睡眠医学 睡眠医学
背景情况:
- 认知能力下降对老龄化人口构成重大全球健康挑战.
- 了解维生素D和睡眠等可改变因素对于保持老年人的认知健康至关重要.
研究的目的:
- 调查血清25-氧维生素D3 (25(OH) D3) 水平和睡眠模式与认知障碍风险的横截面和纵向关联.
- 为了检查25(OH) D3和睡眠对中国老年人的认知功能的潜在相互作用.
主要方法:
- 利用来自中国长度健康长寿调查 (2011/2012, 2014) 的3412名成年人 (65-105岁) 的数据.
- 使用迷你精神状态检查评估认知障碍,睡眠质量 (好与公平/差),睡眠持续时间 (短,正常,长).
- 采用多级和物流回归模型,调整多个共变量.
主要成果:
- 与缺乏相比,维生素D3的充足与认知障碍的风险降低33%.
- 良好的睡眠质量与认知障碍风险降低34%相关.
- 维生素D3的充足显示出协同作用,进一步降低了良好的睡眠质量和正常睡眠时间的个体的认知障碍风险.
结论:
- 适当的维生素D3水平和良好的睡眠质量与老年人的认知功能有关.
- 维生素D3的充足可能会放大健康睡眠模式的认知益处,突出潜在的双重干预策略.
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