为监测汗液中含量变化准备β-环氧的功能化平台
1College of Physical Education, Shanxi University, Taiyuan 030006, China.
Molecules (Basel, Switzerland)
|October 14, 2023
概括
这项研究引入了使用β-cyclodextrin功能化减少石墨烯氧化物 (β-CD-RGO) 的新型印刷电极,用于准确,非侵入性的汗水 (K+) 监测. 开发的可穿戴传感器在运动期间对电解质平衡评估具有很高的选择性和可靠性.
科学领域:
- 电化学 电化学 电化学
- 材料科学 材料科学 材料科学
- 可穿戴式传感器 穿戴式传感器
背景情况:
- 在汗水中对离子 (K+) 的非侵入性监测对于了解电解质平衡和肌肉疲劳至关重要.
- 目前的汗水测试方法复杂,现有的可穿戴传感器受到漂移,污染和离子干扰 (例如Na+) 的影响.
研究的目的:
- 开发使用β-cyclodextrin功能化降解石墨烯氧化物 (β-CD-RGO) 的印刷电极,用于选择性和准确地量化人类汗水中的K+.
- 创建一个稳定的,可扩展的墨水,用于制造可穿戴传感器,用于非侵入性汗水K+检测.
主要方法:
- 在导电碳基板上使用β-CD-RGO墨水制造印电极.
- 材料表征和电化学分析 (循环电压测量) 来确认β-CD功能和电极性能.
- 与聚乙烯 (PVC) 膜集成并测试线性,灵敏度,可重复性和对常见汗液离子的选择性.
主要成果:
- 优化的β-CD-RGO电极表现出增强的电化学行为和对K+的选择性.
- 传感器显示了线性检测范围 (10μM到100mM),具有高灵敏度 (54.7mV/十年) 和最小的Na+干扰.
- 在人体试验中,汗水K +测量和血清分析之间存在强烈的相关性,验证了非侵入性监测能力.
结论:
- 稳定的β-CD-RGO油墨的简单合成使可穿戴传感器的可扩展制造成为可能,用于汗水检测.
- 开发的传感器为非侵入性监测电解质平衡和生理状态提供了一个有希望的平台.
更多相关视频
10:59Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors
Published on: February 10, 2014
10.3K
13:30Use of the Ramsay Assay to Measure Fluid Secretion and Ion Flux Rates in the Drosophila melanogaster Malpighian Tubule
Published on: November 25, 2015
11.9K
相关概念视频
Regulation of Sodium and Potassium
564
The regulation of sodium and potassium ion concentrations in the human body is a complex process governed primarily by hormones such as aldosterone, antidiuretic hormone (ADH), and atrial natriuretic peptide (ANP).
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily...
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily...
564
Antihypertensive Drugs: Potassium-Sparing Diuretics
600
Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the functional unit of the kidney. This heightened activity leads to increased sodium reabsorption and excessive excretion of potassium. To counteract this, potassium-sparing diuretics such as amiloride are used. They function by blocking these sodium channels, thereby reducing the influx of sodium into the epithelial cells and minimizing the loss of...
600
Potentiometry: Membrane Electrodes
596
Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
596
Dialysis
724
Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
724
