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影响牙植入器随机临床试验影响的因素:一本文数分析
Mohamed Ahmed Hassan Mahmoud1, Guilherme Castro Lima Silva do Amaral1, Nathalia Vilela Souza1
1Division of Periodontology, Department of Stomatology, School of Dentistry, University of São Paulo, Sao Paulo, Brazil.
Clinical oral implants research
|October 14, 2023
概括
开放获取和统计学上显著的结果增加了牙科植入物随机对照试验 (RCT) 的引用. 地理来源也影响了引用数量,欧洲的附属机构获得了更多. 大多数RCT显示了一些偏差风险.
科学领域:
- 牙科研究 牙科研究
- 生物医学工程 生物医学工程
- 临床试验中的临床试验.
背景情况:
- 随机对照试验 (RCT) 对于评估牙科植入物治疗至关重要.
- 高影响因素期刊发表有影响力的牙科植入物研究.
- 了解影响引用数量的因素对于研究传播至关重要.
研究的目的:
- 分析牙科植入物RCT中的参考资料和偏差风险.
- 确定影响这些RCT引用数量的因素.
- 评估已发表的牙科植入物RCT的质量.
主要方法:
- 系统地搜索2016-2017年发表在六个高影响力期刊上的RCT的四个数据库.
- 提取25个参考资料和纸张特征.
- 使用RoB2工具和引用分析负二项式回归进行偏差风险评估.
主要成果:
- 150个RCT累计获得了3452个引用.
- 开放式和统计学意义的RCT获得了更多的引用 (分别增加了60%和46%).
- 来自非洲,亚洲和大洋洲的分支机构的引用比欧洲分支机构少49%. 73.3%的人担心,26%的人有偏见的高风险.
结论:
- 开放获取,统计学上显著的发现和作者所属的国家影响牙科植入物RCT引用数量.
- 大多数已发表的RCT都表现出一定程度的偏差.
- 进一步的研究应该考虑这些因素,以改善影响和质量.
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