异常性良性性定位与大脑小血管疾病的相关性
Ting Yu1, Hui Zhang1, Yong-Mei Yan1
1The First School of Clinical Medicine, Shaanxi University of Chinese Medicine, China; Department of Neurology, Affiliated Hospital of Shaanxi University of Chinese Medicine, China.
The American journal of emergency medicine
|October 14, 2023
概括
患有良性性发性位置性 (BPPV) 的老年人表现出大脑小血管疾病 (CSVD) 的更大负担. 这表明血管功能障碍有助于该年龄组的BPPV发展.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 血管医学 血管医学
背景情况:
- 良性发性位置性 (BPPV) 是最常见的外周,血管病变被怀疑是原因,特别是在老年人中.
- 大脑小血管疾病 (CSVD) 涉及小脑血管的损伤.
- 与年龄相关的风险因素和炎症可能会将BPPV和CSVD联系起来.
研究的目的:
- 在50岁及以上的个体中调查BPPV和CSVD之间的相关性.
- 为了确定BPPV患者与对照组相比,是否表现出更高的CSVD负担.
主要方法:
- 50岁以上被诊断患有BPPV的患者和患有异常性面部神经炎 (IFN) 的对照组的回顾性研究.
- 使用法泽卡斯尺度评估的大脑白质过强度 (WMHs).
- 顺序回归分析用于对比BPPV和WMHs.
主要成果:
- 包括101名BPPV患者和116名IFN对照.
- 在BPPV患者中,具有更高Fazekas分数 (OR=2.37) 的可能性显著增加.
- 脑梗塞,高血压和年龄预测的白质激增 (OR分别为9.9,2.86,1.18).
结论:
- 在50岁及以上的个人中,BPPV与白质超强度 (WMHs) 的严重程度之间存在相关性.
- 受衰老和炎症影响的血管功能障碍可能会导致BPPV的发展.
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