2020年肺癌发病率根据组织学亚型的全球变化:基于人口的研究
Yanting Zhang1, Salvatore Vaccarella2, Eileen Morgan2
1Department of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, China.
The Lancet. Oncology
|October 14, 2023
概括
腺癌现在是全球最常见的肺癌亚型. 2020年,腺癌的发病率在大多数国家在男性中超过了状细胞癌,在所有国家在女性中超过了状细胞癌.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 肺癌是全球第二常见的癌症,但其组织学亚型分布以前是未知的.
- 了解亚型分布对于有针对性的预防和治疗策略至关重要.
研究的目的:
- 量化肺癌发病率的全球,区域和国家负担,其四种主要组织学亚型.
- 分析全球腺癌,状细胞癌,小细胞癌和大细胞癌的分布.
主要方法:
- 利用了来自五大洲癌症发病率第十一卷和非洲癌症登记网络的数据.
- 根据国家,性别和年龄评估亚型比例,将其应用于GLOBOCAN 2020估计.
- 重新分配未指定的形态和计算使用世界标准人口的年龄标准化发病率.
主要成果:
- 2020年,腺癌是全球最常见的肺癌亚型 (男性为39%,女性为57%).
- 腺癌的发病率超过了状细胞癌在150/185个国家的男性和所有国家的女性.
- 根据人类发展指数,所有亚型的发病率都呈现出梯度,在高人类发展指数的国家,发病率更高.
结论:
- 腺癌已经成为全球占主导地位的肺癌亚型.
- 这些发现突显了肺癌亚型发病率的区域差异和社会经济梯度.
- 结果促进了定制的国家预防行动,并为全球肺癌控制战略提供了信息.
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