怀孕期间的昏迷,怀孕的直接结果,以及后代的长期神经健康状况
Shani Orenshtein1, Eyal Sheiner2, Ruslan Sergienko1
1Faculty of Health Sciences, Department of Epidemiology, Biostatistics and Community Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Ms Orenshtein, Mr Sergienko, and Dr Wainstock).
American journal of obstetrics & gynecology MFM
|October 14, 2023
概括
怀孕期间产妇昏迷增加了胎儿生长限制和剖腹产的风险. 它还与后代的长期神经系统问题有关,无论昏睡何时发生.
科学领域:
- 产科和妇科 产科和妇科
- 围产儿医学 围产儿医学
- 神经学 神经学
背景情况:
- 有限的数据存在于孕产妇的围产期结局.
- 对后代健康的潜在长期影响基本上是未知的.
研究的目的:
- 为了调查与产前母亲昏迷相关的围产期结局.
- 为了检查长期后代的神经病情.
- 评估怀孕期间昏迷时间的影响.
主要方法:
- 单独分娩的回顾性队列研究 (1991-2021年).
- 多变量分析以混因素进行调整.
- 评估到18岁的后代神经病态.
主要成果:
- 孕产妇 (232,475例怀孕中的0.3%) 与子宫内生长限制 (aOR 1.52) 的风险增加有关,特别是在第一季度.
- 与较高的剖腹产率相关的昏迷 (aOR 1.33).
- 产前昏迷独立地与长期增加的后代神经病率相关 (aHR 1.79).
结论:
- 产前产妇是不良产周结局的独立风险因素.
- 它也是长期后代神经疾病的危险因素.
- 这些风险存在,无论第一个昏迷事件发生在哪个三个月.
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