皮肤交感神经活动在不同房动的消化设置
Chi-Jen Weng1, Cheng-Hung Li2, Yenn-Jiang Lin3
1Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.
Journal of cardiology
|October 14, 2023
概括
传统的导管切除增加了皮肤交感神经活动 (SKNA),与高功率,短期设置不同. 这两种方法都显示出类似的心房的复发率,这表明HPSD可能会减少附带损害.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统研究 自主神经系统研究
- 医疗器械技术 医疗器械技术
背景情况:
- 对心房动 (AF) 的导管切除可以通过调节自主系统来改善.
- 皮肤交感神经活动 (SKNA) 提供了对交感活动的非侵入性评估.
- 关于不同能量设置在AF切除过程中如何影响SKNA的研究有限.
研究的目的:
- 为了研究AF剥离过程中SKNA在不同能量设置中的变化.
- 为了确定SKNA变化和AF切除结果之间的关系.
主要方法:
- 72名AF患者使用常规 (ConV) 或高功率短期 (HPSD) 能量设置进行了导管切除.
- 在射频除之前和之后,测量了右臂的SKNA.
- 分析比较了ConV和HPSD组之间的SKNA变化和1年AF复发率.
主要成果:
- 两组均具有类似的基线SKNA. 在消去后,SKNA在ConV组显著增加 (p=0.003),但在HPSD组没有.
- 在ConV组中,更高的消去后SKNA与没有AF复发相关.
- 一年AF复发率是可比的:ConV为35%,HPSD为28% (p=0.52).
结论:
- 经消去后的SKNA与传统设置相比增加,这表明与HPSD相比,神经调节效应不同.
- 尽管SKNA的反应不同,但两种能量设置的AF复发率在1年内都相似.
- 由于病变深度较小,HPSD策略可能会产生持久性病变,并减少附带损害.
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