干细胞动员中的药物经济问题
1Studio di Economia Sanitaria, Milan, Italy; Biology and Biotechnologies Department "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.
概括
无化疗干细胞动员对于自身外围干细胞移植具有成本效益. 进一步的研究应该为特定的患者群体和医疗保健系统确定成本效益值.
科学领域:
- 血液学 血液学 血液学
- 卫生经济学 卫生经济学
- 在瘤学瘤学.
背景情况:
- 干细胞的动员已经取得了进展,导致了更多的自主外围干细胞移植 (ASCT) 的非手术.
- 越来越多地使用这些程序,需要对其经济影响进行评估.
研究的目的:
- 研究各种干细胞动员策略的成本效益.
- 分析现有的关于干细胞动员在ASCT的经济价值的文献.
主要方法:
- 对2000年至2023年间发表的研究进行了叙事文献综述.
- 在PubMed数据库中进行了搜索,使用关键词与成本效益,非和干细胞动员有关.
- 包含的文章使用两个评估检查清单进行评估.
主要成果:
- 五项研究 (4项成本效益分析和1项成本效益分析) 符合研究标准.
- 大多数包括的研究表明,无化疗干细胞动员是具有成本效益的.
- 诸如研究视角,医疗保健资源估值和敏感性分析等关键要素经常缺失或报告不充分.
结论:
- 从各种角度来看,无需化疗的干细胞动员似乎是一个具有成本效益的方法.
- 未来的研究应该建立局部成本效益值,并探索不同医疗保健系统和患者群体之间的差异.
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