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穿皮冠状动脉干预后由提罗菲班诱导的严重血小板缺血:一个病例报告
Ze-Mu Wang1, Bin Wang2, Ya-Fei Li3
1Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. zemu.wang@njmu.edu.cn.
Journal of medical case reports
|October 14, 2023
概括
铁洛非班是一种糖蛋白IIb/IIIa受体对抗剂,在经皮冠状动脉干预后可能导致严重的血小板缺血. 迅速停止和治疗导致患者的血小板数恢复.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 蒂罗菲班是一种糖蛋白IIb/IIIa受体对抗剂.
- 它被广泛用于穿皮冠状动脉干预 (PCI).
- 严重的血小板缺血是潜在的不良影响.
研究的目的:
- 报告一例由铁洛菲班诱导的严重血小板缩病例.
主要方法:
- 一名76岁的男性患者接受了PCI并接受了tirofiban.
- 在手术后诊断出严重的血小板缺血.
- 治疗包括药物停用,血小板输血和免疫球蛋白G.
主要成果:
- 患者的血小板计数在7天内恢复到正常水平.
- 血小板数从临界低水平增加到112×10^9/L在第5天.
- 患者的血小板数量正常,退院.
结论:
- 泰罗菲班诱导的血小板缺血需要临床意识.
- 及时识别和管理对于患者的康复至关重要.
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