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Updated: Jul 13, 2025

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雄激素受体是黑色素瘤向药物耐药性的决定因素

Anastasia Samarkina1, Markus Kirolos Youssef1, Paola Ostano2

  • 1Department of Immunobiology, University of Lausanne, Épalinges, Switzerland.

Nature communications
|October 14, 2023
PubMed
概括

向雄激素受体 (AR) 可以克服黑色素瘤中对BRAF/MEK抑制剂 (BRAFi/MEKi) 的耐药性. 抑制AR抑制瘤生长并增强抗癌免疫反应在耐性黑色素瘤.

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