韩国成年人体脂肪和骨矿物质密度之间的关联:一个队列研究
Hyunjung Yoon1, Eunju Sung2, Jae-Heon Kang1
1Department of Family Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-Ro, Jongno-Gu, Seoul, 03181, Republic of Korea.
Scientific reports
|October 14, 2023
概括
身体脂肪高,即使BMI正常,也会增加骨质疏松症的风险. 保持健康的身体组成对于骨矿物质密度 (BMD) 的保护至关重要,而不仅仅是体重管理.
科学领域:
- 内分泌学 在内分泌学.
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 身体脂肪和骨矿物质密度 (BMD) 之间的关系是复杂的,挑战了肥胖是保护骨质疏松症的概念.
- 影响人体构成及其对BMD影响的因素需要进一步研究,特别是在多样化的群体中.
研究的目的:
- 调查身体脂肪组成与韩国成年人骨质量下降的发病率之间的联系.
- 为了确定正常的体重指数 (BMI) 和高脂肪率是否会比正常的BMI和正常的脂肪率更大的BMD降低的风险.
主要方法:
- 一项使用韩国成年人参与的康博克三星健康研究 (2012-2019) 数据的队列研究.
- 参与者被分为四组:正常BMI/正常脂肪 (NBMI-NA),正常BMI/高脂肪 (NBMI-HA),超重和肥胖.
- 减少的BMD是由Z-score (≤-2.0) 或T-score (<-1.0) 或骨质疏松症/压缩骨折的诊断定义的.
主要成果:
- 减少骨质量的发病率在正常的BMI与高脂肪 (NBMI-HA) 组 (4.81) 中最高,与正常的BMI/正常脂肪 (NBMI-NA) 组 (3.37) 相比.
- 在调整了混因素后,NBMI-HA组的个体与NBMI-NA组相比, BMD降低的风险明显更高 (危险比率1.47;95% CI1.09-1.99).
- 高体脂百分比 (BFP) 与 BMD 降低的风险增加有关,而不管正常的BMI.
结论:
- 健康的身体组成管理,专注于身体脂肪百分比,对于预防 BMD 降低至关重要.
- 仅仅依靠BMI可能不足以评估骨质疏松症风险;身体脂肪的分布和组成是关键因素.
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