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Updated: Jul 13, 2025

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
09:35

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform

Published on: July 16, 2016

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胰腺β细胞功能和基因表达的动态调节由SND1核心调节器进行in vitro

Sukrati Kanojia1,2,3, Rebecca K Davidson1,2,3, Jason M Conley2,3,4

  • 1Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.

Islets
|October 15, 2023
PubMed
概括

研究人员确定了葡萄球菌核酶和Tudor域含有蛋白质 (SND1) 作为胰腺和十二指肠本体箱1 (PDX1) 的关键合作伙伴. 这种相互作用对胰岛素分泌至关重要,并且在2型糖尿病中受损.

关键词:
同调节器的同调节器SND1 一个人的生活胰岛素分泌 胰岛素分泌转录 转录 是一种转录.转录因子的转录因子2 型糖尿病 2 型糖尿病一个β细胞β细胞.

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