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伊朗不同查杆菌感染的查策略的成本效益分析:基于模型的评估

Mahmood Yousefi¹, Satar Rezaei², Manouchehr Khoshbaten³

¹Department of Health Economics, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran.

|October 15, 2023

概括

使用尿素呼吸试验 (UBT) 查Helicobacter pylori感染是伊朗减少胃癌的最具成本效益的策略. 这种方法在资源限制范围内最大限度地提高了健康益处.

科学领域:

卫生经济学卫生经济学
公共卫生政策公共卫生政策
胃肠病学胃肠病学

背景情况:

胃癌 (GC) 率可以通过查Helicobacter pylori (H. pylori) 感染来降低,这是世界卫生组织推的.
评估H. pylori查策略的成本效益对于伊朗的公共卫生规划至关重要.

研究的目的:

评估和比较伊朗不同H. pylori查策略的成本效益.
确定H. pylori检测的最经济可行的方法,以减轻胃癌风险.

主要方法:

从卫生系统的角度来看,采用了50年的马尔科夫模型.
四种H. pylori查策略 (内镜,血清学,尿素呼吸测试[UBT],便抗原测试[SAT]) 与没有查进行了比较.
模型参数来源于初级数据和已发表的研究,其中包括120名GC患者的成本数据.

主要成果:

所有的H. pylori查策略都产生了更多的质量调整寿命年 (QALYs),而不是没有查.
尿素呼吸试验 (UBT) 策略成为最具成本效益的策略,其增量成本效益比 (ICER) 为每QALY获得的101,106,261.5伊朗里亚尔 (IRR).
概率敏感性分析证实,在伊朗人均GDP支付意愿值下,UBT是最佳策略.

结论:

在伊朗,H. pylori查是一种潜在的成本效益干预措施.
尿素呼吸试验 (UBT) 是评估的最具成本效益的查方法.
未来的研究应该专注于针对特定年龄组的成本效益分析,以优化资源分配.

关键词:

分析成本效益分析.经济评估经济评价胃癌胃癌是一种胃癌.球杆菌的螺旋杆菌.经质量调整的寿命年 (QALY)

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