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Updated: Jul 13, 2025

Sample Preparation for Metabolic Profiling using MALDI Mass Spectrometry Imaging
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Sample Preparation for Metabolic Profiling using MALDI Mass Spectrometry Imaging

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在 hypoxic-ischemic encephalopathy 的情况下通过 MALDI 质谱成像对代谢变化的现场分析

Huihui Liu1, Ting Xie2, Jiyun Wang3

  • 1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.

Talanta
|October 15, 2023
PubMed
概括

低毒性缺血性脑病变 (HIE) 是新生儿脑损伤的主要原因. 这项研究使用MALDI MSI揭示了关键的代谢变化,包括新的甘油三积累,提供了对HIE机制的见解.

关键词:
低毒性-缺血性脑病变是一种脑病变.马尔迪 马尔迪 马尔迪 马尔迪质谱仪成像成像 质谱仪成像这是一个矩阵矩阵.代谢产物的代谢物

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相关概念视频

MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.
Matrix-assisted laser desorption ionization (MALDI) is a commonly...
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