在正常功能的成年人中,萨尔科佩尼亚与功能快速下降和慢性病的关联
Xiaowei Zheng1, Xiao Ren1, Minglan Jiang1
1Public Health Research Center and Department of Public Health and Preventive Medicine, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu214122, People's Republic of China.
The British journal of nutrition
|October 15, 2023
概括
标志着肌肉质量或力量较低的萨科佩尼亚与中国老年人患慢性病 (CKD) 和功能迅速下降的风险较高有关. 早期识别肉类可能有助于预防脏疾病的进展.
科学领域:
- 老年学是一门学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 萨尔科佩尼亚和功能之间的关系还不太清楚.
- 调查这种联系对于患病风险较高的老年人群至关重要.
研究的目的:
- 检查中老年和老年中国成年人中肉类和功能下降和慢性病 (CKD) 之间的关联.
- 为了确定肉类是否会增加快速功能下降或发展CKD的风险.
主要方法:
- 利用来自中国健康与退休长度研究 (2011-2015年) 的数据.
- 包括9375名参与者进行横截面分析和5864人进行纵向分析.
- 根据2019年亚洲萨尔科佩尼亚工作组的标准定义了萨尔科佩尼亚;通过估计的淋巴细胞过率 (eGFRcr-cys) 评估了功能.
主要成果:
- 横截面分析显示了可能的萨尔科佩尼亚和萨尔科佩尼亚与增加CKD风险有关.
- 纵向分析揭示了可能的肉 (OR 1.33) 和肉 (OR 1.49) 增加了快速功能下降或CKD进展的风险.
- 仅仅较低的肌肉质量或强度也增加了对脏不良结果的风险.
结论:
- 在中国成年人中,sarcopenia与慢性病和功能迅速下降的风险增加有显著的关联.
- 肌肉健康是维持功能的一个重要因素,特别是在老年人群中.
- 准皮症可能提供一种新的策略,以防止脏疾病的进展.
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