在健康成年人中最大呼吸压力参考方程以及定义呼吸肌弱的切线点
Ana Lista-Paz1, Daniel Langer2, Margarita Barral-Fernández1
1University of A Coruña, Faculty of Physiotherap, Research Group in Psychosocial Intervention and Functional Rehabilitation, Spain.
Archivos de bronconeumologia
|October 15, 2023
概括
在健康成年人中,最大吸气和呼吸压力 (PImax/PEmax) 的新参考方程式提供了客观的切断点,以定义呼吸肌肉疲软. 这项研究建立了性别特异性值,以帮助临床解释和指导干预.
科学领域:
- 肺部生理学 肺部生理学
- 呼吸系统医学 呼吸系统医学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 最大吸入和呼吸压力 (PImax/PEmax) 对于评估呼吸肌肉强度至关重要.
- 目前的参考方程缺乏明确的切断点来诊断呼吸道肌肉疲弱.
- 确定可靠的参考值对于准确的临床解释至关重要.
研究的目的:
- 在健康成年人中开发PImax/PEmax的性别特定参考方程.
- 确定识别呼吸道肌肉软弱的客观切线点.
- 为评估呼吸道肌肉功能提供标准化工具.
主要方法:
- 一项多中心的横截面研究,涉及西班牙14个中心的610名健康的非吸烟成年人 (年龄18-80岁).
- 使用统一方法进行PImax/PEmax的标准化评估.
- 多重线性回归分析来导出参考方程和T分数以确定弱点的切线点.
主要成果:
- 建立了PImax/PEmax的性别特定参考方程,包括体重指数和年龄.
- 用T-分数 (≥2.5 SD低于峰值平均值) 定义了呼吸道肌肉衰弱的切断点.
- 确定了特定的截止值:PImax (女性:62 cmH2O,男性:83 cmH2O) 和PEmax (女性:81 cmH2O,男性:109 cmH2O).
结论:
- 该研究提供了迄今为止最大的欧洲PImax/PEmax参考值数据集,使用统一的方法.
- 这些新的参考值和切线点有助于识别男性和女性呼吸道肌肉疲软.
- 这些发现将有助于更好地诊断呼吸道肌肉衰弱,并为有关改善呼吸道肌肉功能的干预措施的决策提供信息.
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