在现实世界中偶然的肺结节的结果
Helene Hjorth Vindum1, Katrine Kristensen1, Niels Lyhne Christensen2
1Department of Respiratory Disease and Allergy, Aarhus University Hospital, Aarhus, Denmark.
Clinical lung cancer
|October 15, 2023
概括
通过偶发性肺结节 (IPN) 随访来早期发现肺癌至关重要. 这项研究发现,IPN患者的肺癌发病率为6%,大多数患者被诊断为早期和可治愈的.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 肺癌的早期诊断对于改善患者的生存率至关重要.
- 偶发性肺结节 (IPN) 经常在CT扫描中检测到,可能代表早期的肺癌.
- 管理IPN是资源密集型,需要有效的后续策略.
研究的目的:
- 评估基于CT的随访计划对偶发性肺结节患者的结果.
- 为了确定通过IPN随访检测到的肺癌的发病率.
- 评估接受侵袭性手术的患者比例及其后续结果.
主要方法:
- 在CT IPN后续计划中的患者的回顾性队列研究.
- 数据是从2018年到2021年在阿尔胡斯大学医院收集的.
- 分析包括接受肺针活检的患者.
主要成果:
- 共有4181名IPN患者被跟踪;6% (249) 被诊断为肺癌,其中90%通过IPN随访检测到.
- 75%的肺癌在I-II阶段被诊断出,其中77.9%有资格接受可治愈的治疗.
- 449名患者接受了CT指导的针活检,其中4.5%的IPN总人群在不检测恶性瘤的情况下进行了活检.
结论:
- 在IPN随访计划中,肺癌的累计发病率为6%.
- 在IPN的侵入性手术期间恶性瘤的概率为55.7%,主要是肺癌.
- 大多数确诊的肺癌都处于早期,可能可治愈的阶段,这凸显了IPN随访的价值.
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