在心力衰竭患者中,心房动死亡率趋势
Ramzi Ibrahim1, Vikram J Singh1, Simar J Singh1
1Department of Medicine, University of Arizona-Banner University Medical Center, Tucson, AZ, USA.
概括
由于心脏衰竭 (HF) 的心房动 (AF) 的死亡率不成比例地影响男性,老年人和白人. 年轻的成年人显示死亡率的增加率更高,需要进一步调查和有针对性的干预措施.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 心房动 (AF) 和心力衰竭 (HF) 经常并存并相互恶化,增加患者的发病率和死亡率.
- 了解AF和HF患者的死亡趋势对于公共卫生倡议至关重要.
研究的目的:
- 分析与AF相关的死亡趋势,在被诊断为潜在HF的个体中.
- 为了确定不同的人口和地理分组的AF相关死亡率的差异.
主要方法:
- 对公开可用的CDC数据 (1999-2020年) 的横截面分析.
- 对AF与HF的年龄调整后死亡率的比较,跨年龄,性别,种族/种族和地理分组.
- 逻辑线性回归模型和蒙特卡洛顺序测试被用来计算年平均百分比变化 (AAPC).
主要成果:
- 在美国,共有55,917人死于同伴HF的AF.
- 在男性,老年人,白人人口和非大都市地区观察到更高的年龄调整死亡率.
- 与老年人相比,年轻人死亡率的AAPC显著高于年轻人.
结论:
- 根据年龄,性别,种族和地理位置,AF死亡率在HF患者中存在显著差异.
- 虽然年轻人群的整体死亡率下降,但他们的AAPC较高表明了需要进一步研究的令人担忧的趋势.
- 在患有HF的年轻患者中早期发现AF需要加强预防和治疗策略.
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