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混合生物神经接口用于生物肢体中的应用.

Youngjun Cho1, Hyung Hwa Jeong2, Heejae Shin1

  • 1Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42899, South Korea.

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|October 16, 2023
PubMed
概括
此摘要是机器生成的。

一个新的混合生物接口将生物和神经接口相结合,用于增强假肢控制. 这个系统成功地使用来自行走的子的信号来控制机器人腿,显示了长期的潜力.

关键词:
神经界面的神经界面这是一种神经假肢.再生性的外围神经接口.机器人腿是一个机器人腿.形状记忆的聚合物聚合物.

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科学领域:

  • 生物医学工程 生物医学工程
  • 神经科学是一个神经科学.
  • 康复工程 康复工程 康复工程

背景情况:

  • 先进的神经假肢系统需要复杂的神经控制和感官反.
  • 当前长期的神经接口经常在持续的功能方面面临限制.
  • 可靠的接口对于与生物肢体有效集成至关重要.

研究的目的:

  • 开发和评估一种新的混合生物接口,以改善神经接口.
  • 为了提高神经和生物四肢之间的接口的性能和寿命.
  • 为了实现与神经组织的同时双向通信.

主要方法:

  • 混合接口的制造,集成一个再生外围神经接口 (RPNI) 和一个外围神经接口.
  • 使用形状记忆聚合物扣扣,以简化在切断的神经上的植入.
  • 同时记录和分别刺激神经和RPNI信号.
  • 在子模型中评估接口性能,包括使用自然唤起的信号控制机器人腿.

主要成果:

  • 混合接口成功地记录了来自RPNI和神经的独特信号信息.
  • 分开刺激神经和RPNI诱导了不同的反应,证明了双向控制.
  • 来自行走的子的自然唤起的信号被记录下来,并用于控制机器人腿.
  • 在子中长期评估 (长达29周) 证实了接口的功能和生物相容性.

结论:

  • 新的混合生物界面显著提高了神经界面的性能,用于假肢应用.
  • 记录和利用自然唤起的信号的证明能力为直观的假肢控制提供了一条途径.
  • 接口显示有希望的长期功能和生物相容性,支持其临床翻译的潜力.