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Updated: Jul 13, 2025

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对独特的五环三合成酶TwOSC的结构和催化洞察力

Yunfeng Luo1, Xiaoli Ma2, Yufan Qiu3

  • 1School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.

Angewandte Chemie (International ed. in English)
|October 16, 2023
PubMed
概括

这项研究揭示了植物friedelin合成酶 (TwOSC) 的结构,揭示了复杂friedelin生物合成背后的机制. 确定了关键的残留物,使得突变设计能够提高三烯产量.

关键词:
化-电磁结构结构酶催化酶的催化作用氧化二二烯循环酸.蛋白质工程是指蛋白质工程.QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM

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