阿曼塔丁诱导的角膜:一个病例和文献综述
Antony Raharja1, Wessam Mina1, Zahra Ashena1
1Queen's Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, United Kingdom.
American journal of ophthalmology case reports
|October 16, 2023
概括
长期使用阿曼塔丁可以导致不可逆转的角膜,即使在停止使用后. 这一病例和文献综述强调眼科医生需要在患有不明原因角膜问题的患者中考虑使用阿曼塔丁.
科学领域:
- 眼科医生 眼科 眼科
- 药理学 药理学是指药理学的学科.
- 角膜疾病 角膜疾病
背景情况:
- 常用于帕金森病和流感的药物阿曼塔丁与眼部副作用有关.
- 角膜水腫是一種角膜腫的情況,導致視力模糊和不舒服.
研究的目的:
- 在长期使用阿曼塔丁后报告一个不可逆转的角膜胀病例.
- 审查关于阿曼塔丁诱导的角膜的文献,详细说明其临床表现和结果.
主要方法:
- 介绍了一个双边角膜的患者的案例研究.
- 进行了文献搜索,以识别和分析阿曼塔丁诱导角膜的现有病例报告.
主要成果:
- 患者在使用阿曼塔丁10年后出现严重,不可逆转的角膜,内皮细胞数显著减少.
- 对33例病例的文献综述表明,阿曼塔丁诱导的角膜通常呈现双边,在药物停用后可能会消失,但通常具有持久的低内皮细胞密度.
结论:
- 在无法解释的双边角膜的差异诊断中,应考虑阿曼塔丁.
- 长期使用阿曼塔丁的使用者可能会从定期的查中受益,使用光谱显微镜检测内皮细胞损伤的早期迹象.
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