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以应用程序为基础的评估,对患者的记忆功能,经过输肺性大动脉置换术后的患者

Jonathan Nübel¹, Michael Hauptmann^2,3, Julika Schön⁴

¹Department of Cardiology, University Hospital Heart Centre Brandenburg, Brandenburg Medical School (MHB) Theodor Fontane, Bernau, Germany.

Journal of geriatric cardiology : JGC

|October 16, 2023

概括

跨关动脉置换 (TAVR) 并没有对老年患者的记忆功能产生负面影响. 虽然手术前的记忆低于平均水平,但手术后出现了改善,这可能是由于学习效应.

科学领域:

心脏病学心脏病学
神经学神经学
医疗技术医疗技术医学技术

背景情况:

跨关动脉置换 (TAVR) 是老年患者的标准,有大动脉狭窄.
潜在的风险包括血液动力学不稳定性和脑栓塞,影响神经认知功能和痴呆.
目前的认知测试具有挑战性;人工智能辅助工具提供诊断和监控优化.

研究的目的:

评估TAVR对神经认知功能,特别是记忆力的影响.
评估人工智能辅助应用程序对TAVR患者认知评估的实用性.

主要方法:

通过使用人工智能驱动的"Delta-App"和心理测试来评估神经认知功能.
通过CERAD单词列表和数字跨度任务 (DST) 评估的内存在TAVR前和释放前.
该研究已登记在德国临床试验登记册 (DRKS00020813).

主要成果:

在2020年10月至2022年3月期间招募了141名患者 (平均年龄为81±6岁,42.6%为女性).
在TAVR前,记忆功能低于年龄和教育水平的平均水平.
在CERAD词汇列表回忆 (P < 0.001) 和重复中观察到的显著改进,在DST没有变化.

结论:

尽管手术前存在缺陷,TAVR并没有导致记忆功能的总体下降.
在词汇列表测试中观察到的改进很可能归因于学习效应.
人工智能辅助认知评估显示了TAVR患者监测的潜力.

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