除了与怀孕相关的深静脉血栓症和全腿超声波外
Anna L Parks1, Masarret Fazili2, Valerie Aston3
1Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Research and practice in thrombosis and haemostasis
|October 16, 2023
概括
阴性全腿压缩超声波 (CUS) 对于怀疑深静脉血栓 (DVT) 的孕妇是安全的. 这种诊断策略在随访期间显示DVT事件的发生率很低.
科学领域:
- 医学诊断 医学诊断 医学诊断
- 产科和妇科 产科和妇科
- 血管医学 血管医学
背景情况:
- 深静脉血栓 (DVT) 是怀孕期间的一个重大问题.
- 关于怀孕女性怀疑DVT的最佳诊断方法的数据有限.
研究的目的:
- 为了评估症状性DVT的发生率,在全腿压缩超声波 (CUS) 阴性后的90天内进行.
- 评估怀孕患者在阴性CUS后扣留抗凝药的安全性和有效性.
主要方法:
- 一项前性队列研究,涉及怀孕患者怀疑患有DVT.
- 进行全腿CUS,如果结果为阴性,则暂停抗凝药.
- 主要结局:客观证实DVT,肺栓塞或静脉血栓塞 (VTE) 相关的死亡在90天内.
主要成果:
- 全腿CUS仅在2.1%的病例中发现了DVT; 97.9%的结果正常.
- 在没有接受抗凝血药物的186名阴性CUS患者中,发生了2次DVT事件 (1.1%的发病率).
- 由于行政原因,该研究在计划中的全部积累之前提前终止.
结论:
- 单个阴性全腿CUS似乎是怀孕患者怀疑DVT的低风险策略.
- 需要进一步进行足够强大的研究来确认CUS的作用,可能与前测试概率得分或D-二次体测试相结合.
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