儿童和青少年中偏头痛的特征与普遍的关节高移动性:一个病例对照研究研究
Ankita Ghosh1, Paul S Horn1, Marielle Kabbouche Samaha1
1Division of Neurology (AG), Le Bonheur Children's Hospital, Memphis, TN; Division of Neurology (AG, PSH, MKS, JK, SLL, SW, ADH), Cincinnati Children's Hospital; Department of Pediatrics (PSH, MKS, JK, SWP, ADH), University of Cincinnati College of Medicine; and Division of Behavioral Medicine and Clinical Psychology (SWP), Cincinnati Children's Hospital Medical Center, OH.
综合性关节多动性 (GJH) 与儿童和青少年中更严重的偏头痛症状有关. 这项研究发现,GJH患者的恶心,语音恐惧症增加,PedMIDAS得分更高.
科学领域:
- 儿科神经学 儿科神经学
- 类风湿病学 类风湿病学
- 疼痛管理 疼痛管理
背景情况:
- 综合性关节多动性 (GJH) 影响5-65%的儿童和青少年.
- 偏头痛是儿童群体中常见的一种神经系统疾病.
研究的目的:
- 调查儿科偏头痛患者普遍关节高移动性 (GJH) 和头痛特征之间的关联.
- 确定GJH是否影响儿童和青少年偏头痛症状的严重程度.
主要方法:
- 一个头痛患者数据库的回顾性病例控制分析.
- 包括5435名5-17岁的参与者,他们患有头痛.
- 使用比顿得分 (≥6) 诊断GJH.
主要成果:
- 31.6%的参与者 (1,719/5,435) 被诊断为GJH.
- 患有GJH的参与者表现出明显更高的恶心率 (73.1%对67.5%) 和语音恐惧症 (87.3%对78.8%).
- 在患有GJH的参与者中观察到更高的PedMIDAS分数 (48.2对41.6),表明偏头痛的影响更严重.
结论:
- 儿科偏头痛患者具有全局性关节高移动性经历更严重的偏头痛特征.
- GJH可能是导致青少年偏头痛严重程度的重要因素.
- 需要进一步的研究来探索潜在的机制和临床影响.
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