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Updated: May 11, 2026

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
13:56

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

在体外转录和处理含有中间序列的酵母tRNA基因

R C Ogden, J S Beckman, J Abelson

    Cell
    |June 1, 1979
    PubMed
    概括

    研究人员对酵母基因进行了转移RNA (tRNA) Trp的测序,发现它含有中间序列. 一个Xenopus卵细胞提取物准确地拼接了这种前体RNA,证明了跨物种拼接能力.

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    相关概念视频

    pre-mRNA Processing02:01

    pre-mRNA Processing

    In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
    Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl guanosine). This 5’ cap helps the...