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在iStent注射W植入器和微内侧带切除术 (ab interno trabeculotomy) 结合在初级开角玻璃眼患者的发光乳化中进行手术结果的比较
Hiromitsu Onoe1, Kazuyuki Hirooka1, Koji Namiguchi2,3
1Department of Ophthalmology and Visual Science, Hiroshima University, Hiroshima, Japan.
Frontiers in medicine
|October 16, 2023
概括
结合的白内障手术与微腹内切除术 (μLOT-Phaco) 和iStent注射W (iStent-Phaco) 显示了相似的结果. 这两种程序都有效地降低了初级开角青光眼患者的眼内压力和青光眼药物需求.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 白内障手术 手术 白内障手术
背景情况:
- 主要开角青光眼 (POAG) 是不可逆转失明的主要原因.
- 结合性白内障手术和绿内障手术的目的是同时治疗这两种疾病.
- 微侵袭性玻璃眼手术 (MIGS) 提供了减少内脏压力的不那么侵袭的替代方案.
研究的目的:
- 在POAG患者中,要比较结合白内障手术与微腹内切除术 (μLOT-Phaco) 与iStent注入W植入 (iStent-Phaco) 的外科结果.
- 在至少6个月的随访后,评估眼内压力 (IOP) 降低,药物使用和并发症率.
主要方法:
- 追溯的多中心比较案例系列,涉及39个μLOT-Phaco眼睛和55个iStent-Phaco眼睛.
- 收集的数据包括手术前和手术后的IOP,玻璃眼药物评分和并发症.
- 通过IOP降低,IOP值或需要重新手术来定义手术成功;使用Kaplan-Meier生存分析进行分析.
主要成果:
- 在μLOT-Phaco和iStent-Phaco组中,在3,6和12个月后,术后IOP和药物评分显著降低 (p < 0.001).
- 在6个月和12个月的成功概率分别为μLOT-Phaco的55.3%和48.4%,iStent-Phaco的45.5%和45.5% (p = 0.38).
- 在iStent-Phaco组中,低血发病率显著下降.
结论:
- 当与POAG的白内障手术相结合时,Microhook ab interno trabeculotomy (μLOT) 和iStent注入W植入带来了相似的外科结果.
- 这两种MIGS程序都有效地减少POAG患者的IOP和药物负担.
- 进一步的研究可能会探索每种手术的长期疗效和特定的患者个人资料.
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