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Updated: Jul 13, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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在临床孤立综合征发生30年后,遗传因素对疾病的进展和严重程度的影响

Nitin Sahi1, Lukas Haider1,2, Karen Chung1

  • 1NMR Research Unit, Queen Square Multiple Sclerosis Centre, University College London Queen Square Institute of Neurology, London WC1N 3BG, UK.

Brain communications
|October 16, 2023
PubMed
概括

遗传因素影响多发性硬化症的进展. 像HLA-DRB1*1501,PVRL2和IRX1这样的特定基因与30年内的疾病严重程度,病变积累和残疾有关.

关键词:
疾病的进展 疾病的进展遗传学 遗传学 遗传学 是一个多发性硬化症多发性硬化症现象型 现象型 是一种现象型.严重程度的严重程度.

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