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Updated: Jul 13, 2025

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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上调的Fcrl5破坏了B细胞的能量,并导致自身免疫性疾病

Chisato Ono1, Shinya Tanaka1, Keiko Myouzen2

  • 1Division of Immunology and Genome Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

Frontiers in immunology
|October 16, 2023
PubMed
概括

类似于Fc受体的5 (Fcrl5) 破坏了B细胞无能反应,这是自我耐受性的关键过程. 这种干扰促进了自身免疫性疾病,突出了Fcrl5作为潜在的治疗点.

关键词:
B 细胞 B 细胞 B 细胞类似于Fc受体的5 (Fcrl5)年龄/自身免疫相关的B细胞.其他类型: anergy anergy这是自身免疫力.免疫耐受性 免疫耐受性

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