老年人肺结核和COVID-19:导致疾病负担更高的因素
Anna Allué-Guardia1, Jordi B Torrelles1,2, Alex Sigal3,4,5
1Population Health Program, Texas Biomedical Research Institute, San Antonio, TX, United States.
Frontiers in immunology
|October 16, 2023
概括
年长的成年人面临着由结核病 (Mycobacterium tuberculosis) 和COVID-19 (SARS-CoV-2) 引起的更大的疾病负担. 伴随性疾病和免疫力下降等因素有助于老年人增加这种脆弱性.
科学领域:
- 呼吸道感染 呼吸道感染
- 免疫学 免疫学 免疫学
- 老年学是一门学科.
背景情况:
- 结核菌菌 (M.tb) 和SARS-CoV-2导致严重的下肺部疾病.
- 尽管有不同的病原体和病原体,但两者都不成比例地影响老年人.
研究的目的:
- 探索老年人中M.tb和SARS-CoV-2疾病负担增加的原因.
- 确定导致老年人严重呼吸道感染的常见因素.
主要方法:
- 审查和讨论有关M.tb,SARS-CoV-2和衰老的现有文献.
- 对影响老年人呼吸系统健康的免疫和环境因素的分析.
主要成果:
- 年长的成年人从M.tb和SARS-CoV-2中经历了更大的疾病严重程度.
- 促成因素包括并发病,肺环境变化,自身免疫和抗体反应减弱.
结论:
- 老年人呼吸道感染的较高负担是多因素的.
- 了解这些驱动因素可以为更广泛的干预措施提供信息,以改善老年人群的健康状况.
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