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Updated: Jul 13, 2025

An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes
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主导阴性HNF1α突变通过调节肝补充因子D来促进肝硬化和炎症

Moke Liu1,2,3,4,5, Luna Liu2,3,4,5, Honglin Guo2

  • 1Department of Endocrinology, Shandong Provincial Hospital, Shandong University, Jinan 250021, China.

iScience
|October 16, 2023
PubMed
概括

肝细胞核因子1-alpha (HNF1A) 变体通过增加补充因子D (CFD) 表达,导致炎症和脂质沉积,导致肝脏肥胖症. 准CFD可能有助于管理非酒精性脂肪肝疾病.

关键词:
分子生物学分子生物学分子生理学分子生理学文字转录学 (Transcriptomics) 是一个学科.

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