与SARS-CoV-2感染相关的状静脉血栓症:一个VALDIG病例控制研究
Pierre Deltenre1,2,3, Audrey Payancé4, Laure Elkrief5
1CUB Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
JHEP reports : innovation in hepatology
|October 16, 2023
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染与脊柱静脉血栓症 (SVT) 有关. 患有SARS-CoV-2和SVT的患者可能面临更高的肠道发作风险,需要手术.
科学领域:
- 血管医学 血管医学
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染和静脉血栓塞 (SVT) 之间的关系尚不清楚.
- 这项研究调查了SARS-CoV-2对SVT呈现和结果的影响.
研究的目的:
- 评估SARS-CoV-2感染与最近的SVT之间的关联.
- 为了确定SARS-CoV-2相关的SVT的特定特征.
- 在SARS-CoV-2感染的背景下评估 SVT 的预后.
主要方法:
- 对27名SARS-CoV-2和SVT患者的回顾性分析.
- 与SARS-CoV-2大流行之前的494名SVT患者进行比较.
- 从12个血管肝病集团 (VALDIG) 中心收集的数据.
主要成果:
- 与SARS-CoV-2相关的SVT通常涉及门静脉.
- 患有SARS-CoV-2和SVT的患者呈现出更高的发烧和呼吸系统症状,淋巴细胞数量较低.
- 与对照组 (2,6%) 相比,在感染SARS-CoV-2的患者 (11%) 中观察到需要切除的肠道梗塞的发生率更高.
结论:
- SARS-CoV-2 感染与 SVT 有关.
- 在SARS-CoV-2患者中,SVT表现出明显的临床特征,包括呼吸道症状和淋巴衰竭.
- 在患有SARS-CoV-2-相关SVT的患者中,肠道发作和随后的切除风险增加.
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