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埃利克西尔和毒理学:一个正在发展的社区
Marvin Martens1, Rob Stierum2, Emma L Schymanski3
1Department of Bioinformatics - BiGCaT, Maastricht University, Maastricht, 6229 ER, The Netherlands.
F1000Research
|October 16, 2023
概括
埃利克西尔毒理学社区将整合欧洲生命科学资源,以推进预测毒理学. 该倡议旨在通过合作努力加强化学风险评估和监管科学.
科学领域:
- 毒理学 毒理学 毒理学
- 计算生物学 计算生物学
- 生物信息学是一种生物信息学.
- 风险评估 风险评估
背景情况:
- 毒理学研究传统上依赖于观测模型,但正在与奥米克和计算方法一起发展.
- 工程材料的日益发展需要为科学和监管目的进行早期的预测评估.
- 作为欧洲生命科学基础设施组织,ELIXIR旨在协调各种研究工作.
研究的目的:
- 建议建立一个新的ELIXIR社区,专注于现代预测毒理学.
- 为这个新社区概述路线图并确定高收益的合作.
- 定义ELIXIR毒理学社区的愿景,并将其与现有的ELIXIR活动整合起来.
主要方法:
- 审查现有毒理学项目 (例如,EU-ToxRisk,diXa) 和ELIXIR平台 (例如,TeSS,Bioschemas) 之间过去的合作努力.
- 根据最初的讨论,为ELIXIR毒理学社区制定提案.
- 举办研讨会,以完善社区路线图,并优先考虑合作.
主要成果:
- 一份白皮书详细介绍了合作努力的成果和ELIXIR毒理学社区的拟议愿景.
- 一个为ELIXIR毒理学社区建立的路线图.
- 列出优先考虑的高影响力的合作项目,以促进社区成长.
结论:
- 埃利克西尔毒理学社区有助于将欧洲生命科学资源与预测毒理学联系起来.
- 这个社区将增强毒理学的预测能力,支持化学风险评估和监管科学.
- 拟议的结构和路线图将指导社区在更广泛的ELIXIR框架内的发展和整合.
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