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一个罕见的单边听力神经病变病例,由质子疗法诱导
Mathilde Hoornaert1, Celine Laurent1, Clement Lelong1
1Otolaryngology-Head and Neck Surgery, Erasme Hospital, Brussels University Hospital (HUB), Brussels, BEL.
Cureus
|October 16, 2023
概括
质子辐射疗法 (PRT) 可以导致儿童单边听力神经病变谱系障碍 (ANSD),这是一个罕见的并发症. 这强调了在接受PRT的儿科患者中需要仔细监测听力.
科学领域:
- 在瘤学瘤学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 辐射瘤学 辐射瘤学
背景情况:
- 听力损失 (HL) 是癌症治疗的常见副作用,通常是由基化疗 (PBC) 或放射治疗引起的.
- 辐射诱导的感觉神经听力损失 (SNHL) 通常是渐进的,永久的和剂量依赖的.
- 质子辐射疗法 (PRT) 的耳毒性作用,特别是在患有中枢神经系统 (CNS) 恶性病的儿科患者中,尚未得到充分证实.
研究的目的:
- 在接受PRT治疗的儿科患者中报告单边听力神经病变谱系障碍 (ANSD) 的病例.
- 强调在接受中枢神经系统或头恶性瘤PRT的患者的听觉监测的重要性.
主要方法:
- 一个四岁的病人的病例报告.
- 对患者涉及PRT的治疗史的审查.
- 审计评估用于诊断ANSD.
主要成果:
- 患者在PRT后发展出单边ANSD.
- 这一案例表明了PRT和ANSD之间的潜在联系.
结论:
- PRT可能导致独特的听力障碍形式,如ANSD.
- 对于接受中枢神经系统或头癌PRT的儿科患者来说,常规的听力监测至关重要,以早期检测和管理听力缺陷.
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