在放射敏感性严重综合免疫缺陷疾病中进行平分体移植
Manpreet Saini1, Alka R Khadwal1, Sayan S Roy1
1Clinical Hematology & Medical Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.
Cureus
|October 16, 2023
概括
严重综合免疫缺陷 (SCID) 是一种致命的婴儿疾病,通过修改的平分异性干细胞移植成功治疗. 这种方法使用了一种新的调节方案和博特佐米布来预防罕见NHEJ1基因突变的患者的移植对宿主疾病.
科学领域:
- 免疫学 免疫学 免疫学
- 遗传学 是一个遗传学.
- 血液学 血液学 血液学
背景情况:
- 严重联合免疫缺陷 (SCID) 是一种危及生命的原发性免疫缺陷疾病.
- 造血干细胞移植 (HSCT) 是SCID的唯一治愈治疗方法.
- 罕见的基因突变会导致SCID,这带来了独特的治疗挑战.
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