抗生素处方指南建议在COVID-19:一个系统的调查
Bradley J Langford1,2,3, Valerie Leung2,4, Jennifer Lo5
1Department of Health Research Methods, Evidence & Impact, McMaster University, Hamilton, Canada.
COVID-19抗生素指南需要改进. 提高指南质量和纳入抗微生物药物管理原则对于打击抗微生物药物耐药性 (AMR) 至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 卫生政策 卫生政策
背景情况:
- COVID-19和抗菌素耐药性 (AMR) 代表着重要的,交叉的全球健康威胁.
- 在COVID-19期间过度使用抗菌剂加剧了AMR危机.
- 抗微生物药物管理对于缓解AMR至关重要,指南发挥着关键作用.
研究的目的:
- 系统地评估COVID-19抗生素处方指南的质量.
- 确定这些指导方针在多大程度上纳入了抗微生物药物管理原则.
- 确定与将抗菌药物管理纳入指导方针相关的因素.
主要方法:
- 对eCOVID-19生活地图推 (RecMap) 进行了系统调查.
- 包含了针对COVID-19的明确抗菌剂使用建议的指南.
- 使用AGREE II和AGREE-REX仪器分别评估了指南和建议的质量.
主要成果:
- 分析了28条指导方针,包括63条建议.
- 准则和建议的质量差异很大.
- 71%的指导方针包含了抗微生物管理概念;传染病专业知识和更高的AGREE-REX分数与此结合有关.
结论:
- 显然需要提高针对COVID-19的抗生素处方指南的质量.
- 改善将抗菌药物管理原则纳入指导方针至关重要.
- 这些发现为开发更好的指导方针提供了洞察力,以解决COVID-19流行病之外的抗生素管理问题.
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