肥胖不会改变中年患有高血压的患者的血管功能和手握运动的血液动力学
Stephen M Ratchford1, Ryan M Broxterman1,2, D Taylor La Salle3
1Geriatric Research, Education, and Clinical Center, George E. Whalen Veteran Affairs Medical Center, Salt Lake City, Utah, United States.
概括
肥胖不会使血管功能恶化或在高血压患者中发挥血液动力学作用. 然而,患有高血压的肥胖患者在休息和运动期间表现出较高的缩血压,需要在体育活动期间仔细监测.
科学领域:
- 心血管生理学心血管生理学
- 运动科学 运动科学
- 肥胖问题研究研究
背景情况:
- 运动等生活方式的修改是控制肥胖和高血压 (HTN) 的关键.
- 关于肥胖和HTN如何相互作用影响运动期间血管和血液动力学反应的理解有限.
研究的目的:
- 为了比较肥胖与非肥胖的HTN患者的血管功能和静止状态和手握运动期间的血液动力学.
- 为了确定肥胖是否加剧高血压患者的血管功能障碍.
主要方法:
- 评估了手臂动脉流介导扩张 (FMD) 对于血管功能.
- 在非肥胖和肥胖的高血压成年人中,在渐进式握手运动 (15-45% MVC) 中测量出血动力学.
- 参与者在此之前至少两周没有服用抗高血压药物.
主要成果:
- 肥胖和非肥胖的高血压群体之间没有明显的口病差异.
- 肥胖个体在基线和运动期间表现出较高的缩血压 (SBP).
- 肥胖群体对运动的血流反应更大,但在考虑工作负载差异时正常化.
- 运动期间的血管导电性和血管扩张在各组之间是相似的.
结论:
- 肥胖不会独立地损害血管功能或在高血压患者中发挥血液动力学作用.
- 在肥胖高血压患者中增加的SBP需要在运动期间进行监测.
- 在适当的预防措施下,运动可能适合在肥胖中年成人中管理HTN.
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