后COVID-19胆管病变的内镜特征及其使用ERCP的管理
Silke Leonhardt1, Donata Grajecki1, Dominik Geisel2
1Department of Hepatology and Gastroenterology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
The American journal of gastroenterology
|October 16, 2023
概括
冠状病毒病后2019年 (COVID-19) 胆管病是一种破坏性胆管状况,通常在重症患者中见到. 内镜逆行胆血管细胞造影 (ERCP) 有助于诊断和管理,通过改善胆固醇病标志物的干预措施.
科学领域:
- 胃肠病学和肝病学 胃肠学和肝病学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 冠状病毒病后2019年 (COVID-19) 胆血管病变是一种严重的胃肠道并发症.
- 这种状况的内镜特征尚未得到很好的定义.
研究的目的:
- 定义COVID-19后胆血管病变的内镜特征.
- 为了澄清内镜逆行胆血管细胞造影 (ERCP) 在治疗这种疾病中的作用.
主要方法:
- 这是一项46名确诊患有COVID-19后胆血管病变的患者的观察性研究.
- 分析了141个ERCP程序,以确定内镜和胆血管学特征.
主要成果:
- 后COVID-19胆管病变呈现为二次硬化胆管炎的破坏性变体,在重症监护的早期出现.
- 典型的特征包括心心的肝内胆道破坏,消失的胆道和胆道成型 (85%).
- 并发症包括肝;预后不佳,无移植生存期为44%.
结论:
- 在诊断,预后和管理COVID-19后胆血管病变方面,ERCP至关重要.
- 干预内镜切除件可以改善胆固醇病变的参数.
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